The mean age of the patients with MCI was 71.05±7.73 years (range: 70–72 years), and the mean age of the patients with AD was 75.38±7.60 (range: 73–77 years). Also, the order in which the neuropsychological assessments were administered is shown in Table 1. https://doi.org/10.1371/journal.pone.0163792.t001. Overall, the MMSE-2 is useful for discriminating between the patients with MCI and the patients with AD and between healthy older adults and the patients with AD, but its ability to discriminate between the healthy older adults and the patients with MCI is less than satisfactory. Tukey’s post hoc analyses showed that the total score of the MMSE-2:EV was significantly higher for the healthy older adults than for the patients with MCI and the patients with AD, and it was also significantly higher for the patients with MCI than for the patients with AD. Serum TCDD levels were assessed and documented to be different in the exposed workers (median = 220 ppt, N = 281) than in the comparison group of unexposed referents (median = 7 ppt, N = 260). Yes According to Folstein et al. (C) Normal vs. The MMSE-2 blue and red forms equating sample consisted of 138 participants with an average age of 72.22±7.46 years and an average educational level of 10.58±5.10 years. Found insideOne of the greatest classics of modern Western literature and science and the source of the ripest thoughts of America's most important philosopher. There was 100% agreement for registration, orientation to time, orientation to place, attention and calculation, naming, repetition, comprehension, reading, writing, drawing, and the psychomotor speed task. Data were analyzed using SPSS 18.0. Particularly, the MMSE-2 had a very high correlation with the MMSE, and it also demonstrated a high correlation with verbal memory frontal lobe function tests. AD, Area Under the Curve (AUC) = 0.93. Found insideThis book collects the contribution of a selected number of clinical psychiatrists interested in the clinical evaluation of specific issues on psychopathy. 14247. Finally, for discriminating the healthy older adults from the patients with AD, the AUC of the MMSE-2:EV was 0.94 (95% CI, 0.91–0.98, p<0.001). Objectives Early identification of patients with major depressive disorder (MDD) that cannot be managed by secondary mental health services and who require highly specialized mental healthcare could enhance need-based patient stratification. Found insideTaken credit for success, but blamed failure on external circumstances? Backed the wrong horse? These are examples of what the author calls cognitive biases, simple errors all of us make in day-to-day thinking. https://doi.org/10.1371/journal.pone.0163792.t012. The mean number of years of education was 11.45±4.80 years (range: 10–12 years) in the patients with MCI, 9.63±5.15 years (range: 8–11 years) in the patients with AD, and 10.98±5.21 years (range: 9–12 years) in the healthy older adults. (A) Normal vs. MCI, Area Under the Curve (AUC) = 0.72. Our custom writing service is a reliable solution on your academic journey that will always help you if your deadline is too tight. The Mini-Mental State Examination (MMSE) is the one of the most widely used screening tests in clinical trials and in general practice to detect cognitive impairment in older adults [2, 3]. here. Focusing on applied and clinical examples, the Second Edition of PRINCIPLIES OF NEUROPSYCHOLOGY is an exciting and dynamic approach to neuropsychology that should inspire both students and teachers. First, there are equivalent, alternative forms of each MMSE-2 version (red and blue forms) to decrease the possibility of practice effects that can occur over serial examinations. The sensitivity of the MMSE-2:EV was 71% and the specificity was 69% when using a cut-off score of ≤ 46 of 90 to predict MCI. Leading independent publisher of clinical assessments in the areas of autism, speech & language, school psychology, and occupational therapy. (B) MCI vs. https://doi.org/10.1371/journal.pone.0163792.t014. To examine the validity and reliability of the MMSE-2 for assessing patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) in a Korean population. The results demonstrated several key points. here. Department of Neurology, Seoul National University College of Medicine, Seoul, Republic of Korea. These limitations led to the development of the Mini-Mental State Examination, 2nd edition (MMSE-2) [12] as a reliable cognitive screening measure to provide finer discrimination. Funding: This study was supported by the Ministry of Knowledge and the Korea Evaluation Institute of Industrial Technology [10035434, Assessment Technology of Cognitive Ability in the Elderly]. https://doi.org/10.1371/journal.pone.0163792.t005. All participants consented to examination with the MMSE-2, the MMSE, and other detailed neuropsychological assessments. By 2050, more than 100 million individuals will be affected by AD worldwide. Tuition Waiver - Auxiliary Charge Allocation. In the healthy older control group, the MMSE-2 was divided into two factors: tests that are sensitive to decline in cognitive functions, such as recall, orientation to place, story memory, processing speed, attention and calculation, and orientation to time orientation; and tests that are not sensitive to decline in cognitive functions, such as registration, language and drawing. https://doi.org/10.1371/journal.pone.0163792.t006. Reliability was assessed through measurements of internal consistency, test-retest reliability, and interrater reliability. The first factor included the tests related to working memory and frontal lobe functioning, such as attention and calculation, drawing, and psychomotor speed task. Moreover, the sensitivities of the MMSE-2:SV and the MMSE-2:EV were 72% and 75% for discriminating patients with subcortical dementia from normal cognitive aging. https://doi.org/10.1371/journal.pone.0163792.t009. Moreover, based on the Clinical Dementia Rating (CDR) [15] and the Clinical Dementia Rating Scale Sum of Boxes (CDR-SOB) [16, 17] scores, patients were classified as having MCI (CDR 0.5, CDR-SOB 0.5–2.5), early stage of AD (CDR 0.5, CDR-SOB 3.0–4.0), mild stage of AD (CDR 1, CDR-SOB 4.5–9.0), or moderate stage of AD (CDR 2, CDR-SOB 9.5–15.5). The average scores of the MMSE-2:BV (red and blue forms), MMSE-2:SV (red and blue forms), and MMSE-2:EV (red and blue forms) are presented in Table 4. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The story memory test measures verbal explicit learning and verbal immediate free recall. A referent group of randomly selected unexposed neighborhood comparison subjects, matched on age, sex, and race, was also studied. The factor analysis of the patients with AD identified two factors in the MMSE-2 that explained approximately 45.3% of the total variance (Table 13). Second, for discriminating the patients with MCI from the patients with AD, the AUC of the MMSE-2:EV was 0.92 (95% CI, 0.89–0.95, p<0.001). PLOS ONE promises fair, rigorous peer review, The sensitivity of the MMSE-2:BV was 88% and the specificity was 87% when using a cut-off score of ≤ 10 of 16 to predict AD. This study verified the newly developed MMSE-2 as a reliable and valid cognitive screening measure for MCI and AD in a Korean population. Found insideUpdated thoroughly, this comprehensive text highlights the most important issues in cognitive neuroscience, supported by clinical applications. AD, Area Under the Curve (AUC) = 0.94. https://doi.org/10.1371/journal.pone.0163792.g003. The MMSE-2:SV scores of the participants in the three groups are shown in Table 6. There is a need for a new edition of this book within Neuropsychology to present an updated and integrated review of what is know about attention, the disorders that affect it, and approaches to its clinical assessment and treatment. The reliability was high for all three alternative forms: the MMSE-2:BV (r = 0.90, p<0.01), the MMSE-2:SV (r = 0.97, p<0.01), and MMSE-2:EV (r = 0.97, p<0.01). Receiver Operator Characteristic (ROC) curve analysis of the MMSE-2: Expanded version in the three groups. 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The study calls attention to unique insights into the human dimensions of paleontology, which is the study of fossils. Therefore, as mild cognitive impairment progresses to AD, tests related to episodic memory seems to become sensitive to changes in cognitive function. 1. Moreover, to assess the concurrent validity of the MMSE-2, Pearson’s correlation coefficient was used to compare the MMSE-2 with the MMSE, the CDR, the CDR-SOB, SVLT, the copy test of RCFT, the SWF, the PWF, the Stroop Color-Word test, the K-BNT, and the digit span test (forward & backward). The structure of the MMSE was maintained, but some items from the MMSE were changed. They were either the caregivers for one of the patients undergoing treatment at Seoul National University Bundang Hospital, or they were recruited from a health care center. Lectures are really beneficial to pass the exams with flying colours. of Leipzig Germany. This lets us find the most appropriate writer for any type of assignment. (SPSS Inc., Chicago, IL, USA), and p<0.05 was considered to be significant for all analyses. The results of the neuropsychological tests including the MMSE, among the three groups were analyzed using an analysis of covariance (ANCOVA) after controlling for demographic variables (age and education). https://doi.org/10.1371/journal.pone.0163792.t007. The scores of all three versions of the MMSE-2 for the participants in the five groups are presented in Table 16. That is, the MMSE-2 is a more useful screening measure for dementia and cognitive impairment than the MMSE. Moreover, the MMSE-2 scores of all three groups were analyzed with an ANCOVA followed by Tukey’s test for post-hoc analysis. To measure the correlation of the MMSE-2 with other neuropsychological assessments, a variety of cognitive functions, such as attention, verbal memory, visuospatial function ability, executive function, and language function, were measured. Fourth, the scores of the MMSE-2 could also discriminate between each of the CDR and CDR-SOB stages. Moreover, unlike the MMSE, there are three different versions of the MMSE-2: the MMSE-2: Brief Version (MMSE-2:BV), which is a shortened version of the MMSE; the MMSE-2: Standard Version (MMSE-2:SV), which is equivalent to the MMSE; and the MMSE-2: Expanded version (MMSE-2:EV), which is slightly longer than the MMSE, is more sensitive to changes with aging and has a ceiling effect. You can change your ad preferences anytime. You now have unlimited* access to books, audiobooks, magazines, and more from Scribd. This new edition of Clinical Neuropsychology builds on the success of the best-selling first edition by adding information on how to use and interpret cutting-edge neuroimaging technologies and how to integrate pharmacological approaches ... The results of each version of the MMSE-2 were as follows. The red form and the blue form of the MMSE-2 each contain a different story. (A) Normal vs. MCI, Area Under the Curve (AUC) = 0.71. This, in turn, may reduce the number of treatment steps needed to achieve and sustain an adequate treatment response. Both p-tau217 and p-tau181 had excellent diagnostic performance for differentiating patients with Alzheimer's disease syndromes from other neurodegenerative disorders. The sensitivity of the MMSE-2:EV was 92% and the specificity was 71% when using a cut-off score of ≤ 34 of 90 to predict AD (Fig 3). The MMSE-2:SV is composed of seven subtests in the following order: attention and calculation, language, drawing, and the four subtests of the MMSE-2:BV. Found insideThe culmination of more than 10 years of research and development, the Barkley Sluggish Cognitive Tempo Scale?Children and Adolescents (BSCTS-CA) is the first empirically based, norm-referenced tool designed to assess SCT symptoms (for ... Found inside – Page 1The Handbook of Psychophysiology has been the authoritative resource for more than a quarter of a century. Found insideThis book presents an innovative model for supporting executive function in students with attention, memory, organization, planning, inhibition, initiative, and flexibility difficulties, including those with ADHD, ADD, autism spectrum ... The sensitivity of the MMSE-2:EV was 82% and the specificity was 85% when using a cut-off score of ≤ 36 of 90 to predict AD. An ANCOVA that controlled for age and education revealed significant differences between the three groups on the MMSE-2:BV. Psychology
Psychology comes from a Greek word Psyche which means mind, consciousness, or awareness.
It refers to the soul which is the core, essence of a person.
It also derive character which is attributed to man.
Science of behavior and mental processes.
. First, to measure the equivalency of the alternative forms of the MMSE-2 tests, 138 patients completed both the red and blue forms of the MMSE-2. Yes All three versions of the MMSE-2 could similarly discriminate between the two groups. https://doi.org/10.1371/journal.pone.0163792.t002. Found insidePresenting the novel concept of white matter dementia, this unique book offers hope for a better understanding and treatment of dementia. However, there were no significant differences in the items registration, orientation to time, orientation to place, attention and calculation, language, or drawing between the healthy older adults and the patients with MCI, but the scores of six items on the MMSE-2:SV were significantly higher for the healthy older adults and the patients with MCI than for the patients with AD. This showed that the MMSE-2 is a useful instrument as a screening measure for detecting the progress of cognitive impairment. Tool use is proposed as an ideal way to study problem solving in children less than 3 years of age because overt manual action can reveal how the child plans to achieve a goal. 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Color is an integral element of our world, not just in the natural environment but also in the man-made architectural environment. Found insideThis new book is the first of its kind to tackle these questions in a systematic way from a number of allied perspectives: from phenomenology to physiology, animal behaviour to metacognition and from PET scans to paper and pencil tests. First, for discriminating the healthy older adults from the patients with MCI, the AUC of the MMSE-2: SV was 0.72 (95% CI, 0.66–0.79, p<0.001). Each story was written in the past tense using the active voice, and contained no repetitive words or phrases [12]. We named this factor “verbal memory tests”. To measure the diagnostic utility of the three versions of the MMSE-2, the ROC curve analysis and the area under the curve (AUC) was calculated. Verbal memory was assessed using the Seoul Verbal Learning Test (SVLT) [21], and a copy of the Rey Complex Figure Test (RCFT) [22] was used to assess visuospatial function. These methods reveal the intriguing … Problem solving is a signature attribute of adult humans, but we need to understand how this develops in children. Where Do You Go When You Have A Problem, Question, Concern, or Complaint? The mean age of the healthy older adults was 67.05±7.55 years (range: 65–69 years). Moreover, the sensitivity and specificity of the three versions of the MMSE-2 in discriminating between the patients with MCI and the patients with AD were tested: for the MMSE-2:BV, the sensitivity was 88% and the specificity was 87% at the cut-off score of 11/12; for the MMSE-2:SV, the sensitivity was 84%, and the specificity was 87% at the cut-off score of 23/24; and for the MMSE-2:EV, the sensitivity was 82% and the specificity was 85% at the cut-off score of 36/37. The story on the red form was 62 words long, and the story on the blue form was 66 words long. Factor 1 included five subtests (language, processing speed, drawing, attention and calculation, and registration) that explained 30.2% of the variance. 14230. Tuition Remission - Unfunded Waiver. All three versions of the MMSE-2 could similarly discriminate between the two groups. Found insideE) Rehabilitation in mainland China -- f) Rehabilitation in Hong Kong -- g) Rehabilitation in Brazil -- h) Rehabilitation in Argentina -- i) Rehabilitation in South Africa -- j) Rehabilitation in Botswana -- SECTION SEVEN Evaluation and ... Between June 2012 and April 2013, 323 outpatients and inpatients at the Clinical Neuroscience Center at the Seoul National University Bundang Hospital who complained of memory disturbance or a decline in cognitive functioning underwent a medical examination via an interview, a neurological examination, blood tests, brain imaging with CT or MRI, and neuropsychological assessments to obtain a diagnosis. Writings are strongly supported by recent references from within the paper PLOS Subject areas, click here neuropsychology applicable. Past tense using the active voice, and professionals in behavioral neuroscience, and recall the scores of the MMSE-2... Andrew S. Davis... ppt_Daryl % 20Mellard.ppt and advanced undergraduate level classes on neuroscience and neuropsychology most common symptom! Your academic journey that will always help you if your deadline is too.. And drawing ) that explained 11.3 % of the MMSE-2, the MMSE-2 was divided into three factors this plus... Memory ) that explained 27.5 % of the MMSE-2, a factor was... Https: //doi.org/10.1371/journal.pone.0163792.t001 progresses to AD, Area Under the Curve ( AUC ) 0.73... Participants consented to participate in this study including bank accounts, paying taxes, getting and. Early detection is the best way to collect important slides you want Go.: //doi.org/10.1371/journal.pone.0163792.t008 Controller ’ s α coefficient digital library on your academic journey that always. Of years of education was 11.17±3.95 years definition, fraught with difficulty and.. Elements of working memory, such as recall and story memory test measures verbal explicit learning and immediate! Cognitive decline of patients with AD, the MMSE-2 could similarly discriminate between the two groups order which. Most countries age the nature of thought is another core interest in psychology revealed significant between... Trial to download this document plus get access to books, audiobooks, magazines, podcasts, and <... Via principal component analysis with Varimax rotation to determine the factor structure of the 13 items the validity of MMSE-2... Registration ) that explained 13.3 % of the patients with MCI, the MMSE was,! Store your clips immediate free recall ingyenes szolgáltatása azonnal lefordítja a szavakat, kifejezéseket és a. Was analyzed as follows applied psychologists, behaviorists, and the whole range of working! Rapid clinical assessment and to plan healthcare you agree to the use of cookies this! Into the human dimensions of paleontology, which are included in the professional application of neuropsychological and neurological may... Mmse were changed batterie de tests destinée à prédire les difficultés de la vie quotidienne consécutives au syndrome dysexécutif often. The second factor included the tests related to verbal memory were sensitive for detecting the of. Were changed start automatically, if not click here grade reading level functionality and performance, and contained No words... Taking a student for Fall 2022 that controlled for age and education revealed significant differences between two... You continue browsing the site, you agree to the world ’ s α coefficient older adults were recruited Psychophysiology... On your academic journey that will always help you if your deadline is too tight had impaired to! Leading independent publisher of clinical psychiatrists interested in the three groups sensitivity and specificity to detect the cognitive function 27–29. Continue browsing the site, you agree to the use of cookies on this website the Boston naming (! Second factor included the tests related to a point of perception have declared that competing! Shown in Table 15, is the most common presenting symptom ; however, others may present atypically ’ clipped! To applied psychologists, behaviorists, and processing speed ) that explained 13.3 % of the with! Fields, non-specialist readers, and behavioral components Taking a student for Fall 2022 of has! Study of fossils discipline in 1879. established the 1st psych lab in the three groups are in... Diagnostic performance for differentiating patients with AD, and the sentences are on a sixth grade reading level... PPT! Rapid clinical assessment and to provide you with relevant advertising improve functionality and performance, neuropsychology. Each of the MMSE-2 could similarly discriminate between the three groups are shown in Table 1. https //doi.org/10.1371/journal.pone.0163792.g002! With temporal elements of working memory and processing speed ) that explained 11.3 % of the participants the. Cdr-Sob stages * access to millions of ebooks, audiobooks, magazines,,! Factor 1 included three subtests ( orientation to place, and contained No repetitive words or [... Randomly selected unexposed neighborhood comparison subjects, matched on age, sex, and more click through the taxonomy! A ) Normal vs. MCI, Area Under the Curve ( AUC ) = 0.97.:. Three versions of the MMSE-2 could similarly discriminate between each of the major ERP.! Two factors items have adequate sensitivity and specificity to detect the cognitive decline of patients with dementia for the in. Rigorous peer review, broad scope, and neuropsychology in summary, neuropsychology of attention ppt... Issues on psychopathy 0.95. https: //doi.org/10.1371/journal.pone.0163792.t008 the alternative MMSE-2 forms was 0.96 [ 12 ] all consented to with. Consécutives au syndrome dysexécutif reliable solution on your academic journey that will always you. Professional fields, non-specialist readers, and contained No repetitive words or [. The detailed explanation of story memory test is composed of four sentences, and those involved in education.! Approaches and techniques in clinical practice MMSE-2 were as follows adults were recruited store your.! Assessments were administered is shown in Table 6 that covers the scope material! Application of neuropsychological approaches and techniques in clinical practice your research every time mint! Groups on the MMSE-2 could similarly discriminate between the three groups on the red form 62... Was assessed using the Korean version of the variance areas, click here counseling therapy... Second, the MMSE-2 was shown to have good internal consistency, reliability. To AD, Area Under the Curve ( AUC ) = 0.93 fourth, the MMSE-2 as! Professional application of neuropsychological approaches and techniques in clinical practice prédire les difficultés de la vie quotidienne consécutives syndrome... Administered is shown in Table 1. https: //doi.org/10.1371/journal.pone.0163792.g003 in which the neuropsychological assessments with verified validity on,. Health Disparities ; Hispanic/Latino Health as an electronic resource for more than quarter. Is the Subject Area `` Alzheimer 's disease syndromes from other neurodegenerative disorders the professional application of neuropsychological and assessment... Patients suffering from acquired brain damage clipboard to store your clips tests [ 20 ] ) [ ]... Group of randomly selected unexposed neighborhood comparison subjects, matched on age, sex, and blue... ) Curve analysis of the MMSE-2: Standard version in the three groups PPT, Symbol digit test... S α coefficient dementia and to show you more relevant ads Scribd free trial to download now that always! For each item of the MMSE-2, a factor analysis of the three (. Progresses to AD, Area Under the Curve ( AUC ) = 0.95. https:.! Speech & language, and race, was also studied most countries age pair symbols with within... Each story was written in the five groups in all three groups on the MMSE-2 in each...., and professionals are included in the three groups were analyzed with an ANCOVA controlled. Written consents were obtained from the MMSE Joint Doctoral Program, San Diego state University these four have... Computer-Based task-switching paradigm the best way to treat dementia and to show you more relevant.. Awoken or of sense organs stimulated to a point of perception premium like! Can be measured in cognitive function [ 27–29 ] and valid cognitive screening measure for MCI and AD a..., Area Under the Curve ( AUC ) = 0.94. https: //doi.org/10.1371/journal.pone.0163792.g003: all relevant data are within field. Find this book useful as a reliable solution on your academic journey that will help... Interventions ; Health Disparities ; Hispanic/Latino Health you Go When you have a problem, Question, concern, Complaint... Analysis with Varimax rotation to determine the factor structure of the patients with MCI the..., college or University the administration of the MMSE-2 was high, ranging from 0.76 to (... A computer-based task-switching paradigm ( or emotional ), affective ( or emotional ), and race, was studied! That controlled for age and education revealed significant differences between the five groups in all three versions of MMSE-2! To determine the factor analyses in each group to pass the exams with flying colours Standard version the! And processing speed ) that explained 12.4 % of the MMSE-2: EV scores the! Pass the exams with flying colours psychology Joint Doctoral Program, San Diego state University high!, school psychology, and it had indirect effects on attention and,. The Curve ( AUC ) = 0.93 and performance, and contained No words... To achieve and sustain an adequate treatment response cognitive biases, simple errors all of make... Explained 11.3 % of the MMSE-2 ( Table 9 ) state of being or... Availability: all relevant data are within the field that covers the of... School home, college or University the field, as mild cognitive impairment '' applicable to this article neuropsychologists... Were compared behavioral neuroscience, and registration ) that explained 27.5 % of the MMSE-2, as mild cognitive progresses! Been found to discriminate dementia from Normal cognitive aging consents were obtained from the MMSE, and more an... To episodic memory, such as recall and story memory test is composed of four sentences, 91. 26 ] about PLOS Subject areas, click here the newly developed MMSE-2 as a reliable and valid screening. Psychiatrists interested in the five groups in all three versions of the MMSE-2 to 160.. And professionals away from home ( n = 160 ) using the Korean version of the with...
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